Graham's group develops SERS-based nanoplasmonic sensing platforms for biomedical applications. Research directions: (1) SERS nanogap substrates β engineering colloidal gold and silver nanostructure clusters with reproducible, high-enhancement nanogaps for single-molecule SERS detection; (2) In vivo SERS β intravenous SERS nanotags for tumor imaging and multiplexed biomarker detection in living organisms; (3) Microfluidic SERS β integrating SERS probes in microfluidic channels for continuous monitoring of circulating biomarkers; (4) Quantitative SERS β calibration strategies for absolute analyte quantification for clinical diagnostics. Extreme sensitivity (single-molecule) relevant to quantum-enhanced optical sensing.
Grange leads the Optical Nanomaterial Group at ETH, developing nonlinear materials for quantum photonic integrated circuits. Research directions: (1) Barium titanate (BTO) nanophotonics β scalable CMOS-compatible BTO thin-film integrated circuits exploiting large Ο(2) nonlinearity for quantum entangled photon-pair generation via SPDC; (2) Lithium niobate on insulator (LNOI) β quantum photonic integrated circuits for heralded single-photon sources and electro-optic transduction; (3) Second-harmonic generation sensing β SHG-active nanocrystals as contrast agents and phase-sensitive probes in biological imaging; (4) On-chip entangled photon sources for quantum communication and sensing. Strong quantum sensing application in nonlinear optical readout of quantum states.
Gregor's Laboratory for the Physics of Life builds custom quantitative microscopes (single-objective oblique-plane light-sheet, multicolor live-imaging, single-molecule transcription imaging) to make precision, physics-style measurements of gene expression, morphogen gradients, and chromatin dynamics in living Drosophila embryos and mammalian gastruloids. He is actively recruiting PhD students and postdocs with expertise in super-resolution imaging, nonlinear/ultrafast optics, and instrumentation development.
Grucker works on optically-pumped, spin-exchange hyperpolarized helium-3 for quantum-fluid physics and biomedical MRI contrast, part of LKB's polarized-helium team that historically bridges fundamental AMO physics with clinical lung-imaging applications.
Gruetter leads the Laboratory for Functional and Metabolic Imaging (LFMI) at EPFL and co-directs the CIBM (Centre for Biomedical Imaging). Research directions: (1) Ultra-high-field in vivo MR spectroscopy β developing 1H, 13C, 31P, 23Na MRS at 14.1T animal and 7T human systems to measure metabolite concentrations (glutamate, GABA, lactate) in brain with unprecedented sensitivity; (2) Quantum coherence effects in NMR β exploiting J-coupling evolution and JPRESS sequences for quantum-selective metabolite editing; (3) Hyperpolarization β DNP-enhanced metabolite sensing in vivo for tracking metabolic flux in real time; (4) Neuroimaging β quantitative BOLD fMRI calibration and cerebral blood flow mapping. The 14.1T magnet is among the world's most powerful for biological NMR spectroscopy.
Kristin GruΓmayer (Assistant Professor, BioNanoscience, 2021) develops super-resolution microscopy tools. Research: (1) SOFI (super-resolution optical fluctuation imaging) β camera-based super-resolution using photon statistics; (2) multi-plane super-resolution and quantitative phase imaging β combined modalities for 3D sub-diffraction imaging; (3) new fluorescence probe classes for SMLM; (4) AI-driven smart microscopy for automated phenotype detection. Marie Curie Fellow (EPFL, Lasser group). Group established 2021.
Gruszka's Chromatin Dynamics Lab combines real-time single-molecule imaging with biochemistry and biophysics (including in Xenopus egg-extract systems) to study how epigenetic information carried by nucleosomes is disassembled and re-established during DNA replication. The lab is actively recruiting postdoctoral fellows.
Gureyev is one of the originators of propagation-based X-ray phase-contrast imaging and the transport-of-intensity phase-retrieval methods that made it practical; his current work concerns the information-theoretic limits of imaging β how signal-to-noise, spatial resolution and radiation dose trade against one another β and the application of those limits to phase-contrast tomography, ptychography and electron microscopy, including biomedical imaging at clinically tolerable dose. Positioned against the established body of NV-ensemble quantum sensing work β DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity β the shared intellectual core is the noise-resolution-dose triangle: the same estimation-theory framework that sets the pT/sqrt(Hz) floor of an NV ensemble governs how many photons a phase-contrast image needs. Borderline inclusion (X-ray rather than quantum sensing), kept because the technique is explicitly about pushing resolution past conventional limits.
Ham's group builds CMOS integrated-circuit platforms spanning scalable, chip-based NMR spectrometers (including impedance-tuned microwave loops for controlling dense NV-diamond spin ensembles, developed with Ronald Walsworth) and CMOS intracellular microelectrode arrays that record from thousands of neurons in parallel β a dual quantum-sensing/bioelectronic-sensing program built around scaling sensitive spin- and electrode-based sensors onto integrated circuits.
Develops microfluidics and imaging-based spatial-omics technologies for high-resolution, high-throughput assays and modeling of complex biological systems, including bottom-up construction of synthetic cells.