Gruetter leads the Laboratory for Functional and Metabolic Imaging (LFMI) at EPFL and co-directs the CIBM (Centre for Biomedical Imaging). Research directions: (1) Ultra-high-field in vivo MR spectroscopy — developing 1H, 13C, 31P, 23Na MRS at 14.1T animal and 7T human systems to measure metabolite concentrations (glutamate, GABA, lactate) in brain with unprecedented sensitivity; (2) Quantum coherence effects in NMR — exploiting J-coupling evolution and JPRESS sequences for quantum-selective metabolite editing; (3) Hyperpolarization — DNP-enhanced metabolite sensing in vivo for tracking metabolic flux in real time; (4) Neuroimaging — quantitative BOLD fMRI calibration and cerebral blood flow mapping. The 14.1T magnet is among the world's most powerful for biological NMR spectroscopy.