Research Areas - (3) SOFI / SMLM Super-Resolution with Fluorescent Probes

Full path: Physics > Quantum Sensing > Nanodiamonds > SOFI / SMLM Super-Resolution with Fluorescent Probes

Department(s)/lab(s): BioNanoscience / Kavli Institute of Nanoscience | Kristin Grußmayer Lab β€” Super-Resolution Microscopy @ TU Delft
Summary:

Kristin Grußmayer (Assistant Professor, BioNanoscience, 2021) develops super-resolution microscopy tools. Research: (1) SOFI (super-resolution optical fluctuation imaging) β€” camera-based super-resolution using photon statistics; (2) multi-plane super-resolution and quantitative phase imaging β€” combined modalities for 3D sub-diffraction imaging; (3) new fluorescence probe classes for SMLM; (4) AI-driven smart microscopy for automated phenotype detection. Marie Curie Fellow (EPFL, Lasser group). Group established 2021.

Department(s)/lab(s): Electrical & Computer Engineering | Hemmer Quantum Photonics Laboratory @ TAMU
Summary:

Hemmer pioneered NV-diamond spin sensing and super-resolution with spin defects, working on coherent control, photonic integration of NV sensors, and diamond-based magnetometry/imaging bridging physics and engineering. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is directly in the NV ensemble sensing lineage, emphasizing photonic integration and super-resolution readout.

Department(s)/lab(s): Physics | LuMIn - NV & Nanodiamond Biosensing (Treussart) @ ENSPS
Summary:

Treussart uses fluorescent nanodiamonds (NV centres) as photostable bio-probes: intracellular single-particle tracking, nanoscale thermometry/magnetometry, and multimodal biosensing in cells and organisms, alongside super-resolution imaging - a direct NV-ensemble-to-biology bridge. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is applied here to living cells via nanodiamond probes.