Ananthanarayanan was awarded the Royal Microscopical Society Life Sciences Award in 2025 for the use of novel microscopies in cell biology. Her group images individual motor proteins — dynein, kinesin — and the mitochondria they transport, in living cells, at single-molecule sensitivity, combining light-sheet and TIRF-class imaging with particle tracking to ask how organelle positioning and mitochondrial dynamics are controlled. The methodological emphasis is on getting single-molecule sensitivity inside a live cell rather than in vitro, which is the hard version of the problem. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — this is the closest thing at UNSW to a biological end-user for an in-cell quantum sensor: the mitochondrial systems she studies are precisely where NV nanodiamond thermometry and free-radical relaxometry at pT/sqrt(Hz) have been aimed, and she has the live-cell imaging infrastructure to validate any such measurement independently.

Booth's Dynamic Optics and Photonics Group develops adaptive-optics methods (deformable mirrors, spatial light modulators) for aberration correction in confocal, two-photon and super-resolution (STORM/STED/SIM) microscopy, enabling higher-fidelity deep-tissue biomedical imaging, alongside applications in ultrafast laser micro-fabrication of photonic devices.

Paterson develops adaptive-optics and wavefront-sensing techniques to correct optical aberrations in fluorescence microscopy and imaging through complex/turbid media, improving resolution and depth in biological and biomedical imaging.

Tuthill is the world's leading practitioner of aperture-masking interferometry and its modern photonic successors. His group's instruments — GLINT (a photonic nuller that destructively interferes starlight on a chip), Dragonfly, and the kernel-phase analysis framework — exist to recover structure at and below the formal diffraction limit of the telescope, in the photon-starved, speckle-dominated regime where naive imaging fails. Science targets are the dusty pinwheel nebulae of Wolf-Rayet binaries, protoplanetary discs and direct detection of exoplanets. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — this is the astronomy entry in the search that most closely mirrors the intellectual structure of quantum sensing: the instrument's performance is set by a fundamental noise floor (photon and speckle noise, analogous to the shot-noise floor at pT/sqrt(Hz)), and the entire game is designing an estimator and a hardware front end that saturate it. Preferred attribute strongly present.

Upadhyayula (trained with Eric Betzig at Janelia) develops multifunctional adaptive-optical super-resolution microscopy and the large-scale computational pipelines needed to reconstruct terabyte- to petabyte-scale 3D subcellular dynamics datasets. The group is actively recruiting postdocs.