PIs

Associate Professor, EMBL Australia Group Leader, University of New South Wales 🔗
Status: unreviewed revisit date: None Application status: none LOR status: not_needed
Department(s)/lab(s): EMBL Australia Node in Single Molecule Science, UNSW Medicine and Health | Ananthanarayanan Cell Biology and Advanced Microscopy Group @ UNSW
Summary:

Ananthanarayanan was awarded the Royal Microscopical Society Life Sciences Award in 2025 for the use of novel microscopies in cell biology. Her group images individual motor proteins — dynein, kinesin — and the mitochondria they transport, in living cells, at single-molecule sensitivity, combining light-sheet and TIRF-class imaging with particle tracking to ask how organelle positioning and mitochondrial dynamics are controlled. The methodological emphasis is on getting single-molecule sensitivity inside a live cell rather than in vitro, which is the hard version of the problem. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — this is the closest thing at UNSW to a biological end-user for an in-cell quantum sensor: the mitochondrial systems she studies are precisely where NV nanodiamond thermometry and free-radical relaxometry at pT/sqrt(Hz) have been aimed, and she has the live-cell imaging infrastructure to validate any such measurement independently.

Created at: July 12, 2026, 1:04 a.m. Updated at: July 12, 2026, 1:04 a.m. Metadata: Fresh 2026-07-11. Primary lab: cell biology and advanced microscopy, EMBL Australia Node in Single Molecule Science. RMS Life Sciences Award 2025.