Jones's group develops optical tweezers instrumentation for biological applications. Research directions: (1) Single-cell mechanics โ using optical traps to apply calibrated forces to cells and measure viscoelastic properties relevant to cancer invasion and immune response; (2) Motor protein biophysics โ measuring force-velocity curves of kinesin/myosin motors at the single-molecule level; (3) Optical sorting โ holographic optical tweezers for cell sorting by mechanical phenotype; (4) Instrument development โ fast-switching AOD-based traps, quantitative phase imaging combined with force measurement. Sensitive to pN forces, combining biosensing with fundamental biophysics.
Morton directs UCL's Quantum Science and Technology Institute and is Deputy Director of the Q-BIOMED hub. His group manipulates electron and nuclear spins in nanoscale materials (silicon donors, diamond defects) to build quantum sensors, quantum memories, and quantum computing hardware, and within Q-BIOMED is pursuing magnetic-resonance quantum sensing at the single-cell level. He is also a co-founder of the quantum computing spinouts Quantum Motion and Phasecraft.
Nguyen's group at UCL (based at Royal Institution) focuses on magnetic and fluorescent nanoparticles for biomedical sensing and therapy. Research directions: (1) Magnetic nanoparticle synthesis โ iron oxide (SPION) and other magnetic nanoparticles with controlled size, shape, and surface chemistry for MRI contrast and magnetic hyperthermia; (2) Biosensing platforms โ functionalized nanoparticles as MRI-detectable sensors for specific biomolecular targets; magnetic particle imaging (MPI) for real-time tracking; (3) Plasmonic nanoparticles โ gold nanoparticles for optical biosensing and photothermal therapy; (4) Fluorescent nanoparticles โ QD- and dye-conjugated probes for live-cell imaging. Relevant to quantum sensing through magnetic nanoparticle platforms.
Olaya-Castro leads theoretical research on quantum phenomena in biological systems. Research directions: (1) Quantum coherence in photosynthesis โ open quantum systems theory for energy transfer in light-harvesting complexes, probing whether quantum coherence provides functional advantage; vibronic coupling models for chromophore-protein complexes; (2) Counting statistics and noise in exciton and charge transfer; (3) Quantum thermodynamics of biomolecular machines โ efficiency limits and entropy production in molecular motors; (4) Non-classical features of electronic/vibrational dynamics in chromophores; (5) Connections between quantum information measures and biological function. Collaborates with Bain and Llorente-Garcia on joint experiment/theory biosensing projects. Theoretical work only โ no experimental activity.
Renzoni's group is internationally recognized as a pioneer in electromagnetic induction imaging (EMI) with optical atomic magnetometers. Research directions: (1) All-optical 87Rb atomic magnetometer MIT โ demonstrated first magnetic induction tomography (MIT) with atomic magnetometers (2013), first EMI of biological tissues below the 1 Smโปยน threshold (Applied Physics Letters 2020), enabling non-invasive cardiac conductivity imaging; (2) Unshielded RF atomic magnetometer operation with general regression neural network auto-optimization; (3) Non-destructive evaluation โ industrial corrosion/defect imaging via quantum-sensitive MIT; (4) Sub-Fourier signal processing with nonlinear systems for frequency resolution beyond classical limits. Collaborates with NPL on quantum sensing standards. Applications span medicine (atrial fibrillation), security, and materials inspection.