Develops second- and third-harmonic generation (SHG/THG) nonlinear optical microscopy to image collagen and other non-centrosymmetric structural proteins label-free in tissue, with applications to cancer diagnosis and fibrosis, pushing spatial/orientational resolution of structural imaging in intact tissue.
Curmi is a structural and single-molecule biophysicist whose most-cited work is on the light-harvesting antenna proteins of cryptophyte algae, where he and collaborators reported long-lived electronic coherence at ambient temperature — one of the founding results of the quantum-biology field and still one of its most argued-over. His group determines the structures of these antenna complexes and engineers them, and separately works on protein-based molecular motors and on single-molecule fluorescence and FRET measurements of conformational dynamics. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — Curmi supplies the biological systems in which quantum coherence is actually claimed to matter; a pT/sqrt(Hz)-class spin sensor capable of watching radical-pair or exciton dynamics in situ would be aimed at exactly the questions his structures raise. Preferred attribute present: genuine quantum-biology substrate rather than a quantum-flavoured metaphor.
Research focuses on quantum dynamics and excited-state reactivity in biological and synthetic light-harvesting systems. Discovered long-lived quantum coherence in photosynthetic light-harvesting complexes (FMO, 2007). Develops 2D electronic spectroscopy techniques to probe excitonic transport, open quantum systems, and photochemical reaction dynamics on femtosecond timescales. Director NSF QuBBE; co-director Berggren Center for Quantum Biology and Medicine.
Fayer's group develops and applies ultrafast 2D infrared spectroscopy to resolve structural dynamics of water, proteins, and complex fluids on femtosecond-to-picosecond timescales, pushing the temporal resolution of vibrational spectroscopy well past what linear methods can access.
Fleming pioneered two-dimensional electronic spectroscopy and used it to reveal long-lived quantum coherences in photosynthetic light-harvesting complexes, work that reframed how energy transfer efficiency in natural and artificial light-harvesting systems is understood.
Prof. Gaynor (Chemistry, joined summer 2023) develops cutting-edge ultrafast spectroscopy at the physics-chemistry frontier. Directions: (1) Attochemistry — new ultrafast laser spectroscopies operating on attosecond to femtosecond timescales to directly measure how electron spin and orbital motion couple to molecular geometry (spin-vibronic coupling) in chiral molecules and materials of interest for energy conversion and spintronics; (2) Multidimensional nonlinear spectroscopy (2D electronic spectroscopy, 2D vibrational) to track energy and charge transfer immediately after photoexcitation; (3) Instrumentation-first approach: building novel attosecond transient absorption and correlation spectroscopy apparatus from scratch, enabling entirely new observables (e.g., electron-nuclear and spin-orbital correlations). INQUIRE faculty affiliate. Beckman Young Investigator 2025 ($600k, 4 yrs); Packard Fellow 2025 ($875k, 5 yrs).
Kassal is the leading Australian theorist of quantum effects in light harvesting. He established the distinction between coherent processes and coherent states in photosynthesis — showing that under incoherent sunlight at steady state, wavelike motion per se does not enhance efficiency, while environment-assisted transport and supertransfer genuinely can — and has since developed a classification of the mechanisms by which coherence (excitonic, vibrational, or of the light field itself) can improve energy transport. He also pioneered quantum-computer algorithms for chemistry. A distinct and directly relevant thread is the theory of spectroscopy with non-classical light: what entangled or squeezed photons can reveal about molecular coherence that classical light cannot. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — his work is the theoretical counterpart to the quantum-biology ambitions of the NV community: where NV ensembles at pT/sqrt(Hz) try to detect the magnetic signatures of biological spin chemistry, Kassal asks what quantum coherence is actually doing in those systems and whether quantum light can interrogate it.
McCamey is, for a candidate coming from NV ensemble sensing, the single most methodologically adjacent PI at UNSW. His laboratory does optically and electrically detected magnetic resonance on spins that are not defects in diamond: photogenerated spin-correlated radical pairs, triplet excitons in organic semiconductors, singlet-fission intermediates, and molecular spin systems. The instrumentation is the same toolkit — pulsed EPR, ODMR, dynamical decoupling, relaxometry — applied to systems where the spin is created by light and reports on chemistry. He directs the UNSW node of ARC Exciton Science. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — his group runs precisely those pulse sequences (Hahn echo, DEER, relaxometry) on a different spin species, and radical-pair spin chemistry is one of the few plausible mechanisms by which biology could be genuinely quantum — which makes this a strong landing spot for someone wanting to keep the NV skill set but change the physical system. Preferred attributes present: sensitivity-limited spin measurement, quantum-biology relevance.
Olaya-Castro leads theoretical research on quantum phenomena in biological systems. Research directions: (1) Quantum coherence in photosynthesis — open quantum systems theory for energy transfer in light-harvesting complexes, probing whether quantum coherence provides functional advantage; vibronic coupling models for chromophore-protein complexes; (2) Counting statistics and noise in exciton and charge transfer; (3) Quantum thermodynamics of biomolecular machines — efficiency limits and entropy production in molecular motors; (4) Non-classical features of electronic/vibrational dynamics in chromophores; (5) Connections between quantum information measures and biological function. Collaborates with Bain and Llorente-Garcia on joint experiment/theory biosensing projects. Theoretical work only — no experimental activity.
Rao's group uses ultrafast (sub-20 fs) transient absorption and vibronic spectroscopy to study quantum-coherent energy and charge transfer processes in molecular and nanoscale semiconductor systems, most notably the quantum-coherent mechanism of singlet exciton fission, with applications to next-generation photovoltaics.