Technique - (3) Lensless fiber-bundle endoscopic imaging

Type: Experimental

Description: Ultrathin, lens-free endoscopic imaging through a multimode or multicore optical fiber using wavefront control, for minimally invasive deep-tissue microscopy.

Department(s)/lab(s): School of Physics | Nanophotonics and Electromagnetic Materials Group @ USyd
Summary:

Fleming pioneered microstructured polymer optical fibre and continues to work on specialty fibre fabrication: drawing exotic polymer, hybrid polymer-metal and poled-silicate structures that would be impossible in conventional silica, and using them to build metamaterials and biomedical photonic devices including fibre-based sensors and probes. The fabrication route — preform drawing — gives access to geometries and material combinations that lithography cannot reach. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — the relevance to a sensing postdoc is delivery and packaging: fibre-integrated probes are the standard way to get an NV or vapour-cell sensor into a biological or field environment while preserving its pT/sqrt(Hz) sensitivity. Borderline inclusion; senior PI, fabrication-led.

Department(s)/lab(s): School of Physics / Sydney Institute for Astronomy | Sydney Astrophotonic Instrumentation Laboratory (SAIL) @ USyd
Summary:

Leon-Saval co-invented the photonic lantern and is the fibre-device engineer of the SAIL programme. His group designs, draws and characterises multicore fibres, mode-selective lanterns, OH-suppression fibre Bragg gratings and hexabundles, and increasingly applies the same devices outside astronomy — in telecommunications space-division multiplexing and in medical endoscopy and imaging through fibre. The unifying technical problem is coupling a spatially-incoherent, aberrated beam into single-mode circuitry without losing photons. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — photonic lanterns are directly applicable to quantum sensing readout: the same device that feeds a seeing-limited telescope beam into a single-mode spectrograph can feed fluorescence from a scattering biological sample into a single-mode quantum-limited detector, preserving the photon budget that a pT/sqrt(Hz) NV measurement depends on.

Department(s)/lab(s): Engineering | Institut Fresnel - MOSAIC Biophotonics Team @ CNRS
Summary:

Rigneault leads the MOSAIC team at Institut Fresnel, developing label-free nonlinear optical microscopy (CARS/SRS) for chemically-specific imaging of lipids and biomolecules in tissue, and pioneering lensless, hair-thin fiber-bundle endoscopes based on wavefront control for minimally invasive deep-tissue and in vivo biological imaging. He holds 17 patents in optical engineering and molecular spectroscopy for the life sciences.