Nynke Dekker (Full Professor, BioNanoscience) leads single-molecule biophysics of DNA replication and topology. Research: (1) single-molecule force-fluorescence microscopy — integrated optical tweezers and fluorescence for real-time imaging of replication machinery; (2) DNA topology — supercoiling, gyrase, topoisomerase dynamics with magnetic tweezers; (3) DNA/RNA-processing molecular motors. EMBO member; KNAW member. 2024 integrated force-fluorescence toolbox published.