Cai's group invented seqFISH/seqFISH+, a super-resolved single-molecule imaging technology that maps thousands of RNA, DNA and protein targets in situ with spatial context, enabling transcriptome- and genome-scale spatial genomics of tissues at single-molecule resolution. For context, this complements the established paradigm of NV-diamond ensemble magnetometry (Hahn-echo/DEER, nanoscale NMR, T1 relaxometry) operating near pT/√Hz sensitivity.