Research Areas - (2) Reversibly Photoswitchable Fluorescent Protein Imaging

Full path: Biology > Biophysics > Quantum Biology / Biosensing > Super-resolution Microscopy > Reversibly Photoswitchable Fluorescent Protein Imaging

Gerard Marriott 🔗
University of California, Berkeley 🔗
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Department(s)/lab(s): Bioengineering | Marriott Lab @ UCB
Summary:

Marriott engineers reversibly photoswitchable fluorescent and bioluminescent proteins and uses optical lock-in detection to achieve high-contrast, super-resolution imaging of specific proteins deep within scattering tissue.

Remi Metivier 🔗
Ecole Normale Superieure Paris-Saclay 🔗
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Department(s)/lab(s): Chemistry | PPSM - Single-Molecule Photochemistry (Metivier) @ ENSPS
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Metivier (PPSM) studies photochromic and fluorescent molecules at the single-molecule level - photoswitching kinetics, energy transfer and orientation-resolved imaging - underpinning super-resolution (RESOLFT/STORM-type) probes and molecular sensors. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is paralleled by molecular photoswitches enabling optical super-resolution.