Research Areas - (2) Bacterial Single-Molecule PALM Tracking of Cytoskeletal Dynamics

Full path: Biology > Biophysics > Quantum Biology / Biosensing > Super-resolution Microscopy > 3D Single-Molecule Localization Microscopy > Bacterial Single-Molecule PALM Tracking of Cytoskeletal Dynamics

Ethan Garner 🔗
Harvard University 🔗
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Department(s)/lab(s): Molecular and Cellular Biology | Garner Lab @ Harvard
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Garner uses high-resolution, single-molecule tracking and localization microscopy (PALM-based) to study the dynamic spatial organization of the bacterial cytoskeleton and cell-wall synthesis machinery in live prokaryotic cells at nanometer precision.

Joshua Shaevitz 🔗
Princeton University 🔗
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Department(s)/lab(s): Physics | Shaevitz Lab @ Princeton
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Shaevitz combines custom super-resolution and multifocal/3D imaging instrumentation with single-molecule tracking to make precision measurements of bacterial cell-shape mechanics, cytoskeletal dynamics (e.g. MreB), collective motility and pattern formation, and animal behavior quantification. His lab pioneered 3D live-cell imaging of bacterial shape during growth and continues to develop chromatic multifocal and localization-microscopy instrumentation in collaboration with the Yang and Gregor labs.