Staggs is PI of the Atacama Cosmology Telescope (Advanced ACTPol) and co-Director of the Simons Observatory, leading development and production of very large, sensitive cryogenic transition-edge-sensor (TES) focal-plane detector arrays used to map cosmic microwave background temperature and polarization anisotropies at ever finer angular resolution. This is included as an astronomy pivot on the strength of its quantum-limited cryogenic detector instrumentation, which is the enabling technology for the high spectral/spatial resolution CMB science.

Develops instrumentation for cosmic microwave background telescopes and radiometers, including work related to CMB-S4 and 21-cm cosmology experiments.

Builds radio and mm-wave quantum-limited sensing instruments for high-energy astrophysics and cosmology. Directions: (1) PUEO — balloon-borne radio Cherenkov (Askaryan) detector for ultra-high-energy cosmogenic neutrinos; (2) RNO-G — ground-based radio neutrino array at Summit Station, Greenland; (3) UHE cosmic ray radio detection methodology; (4) CMB instrumentation (BICEP/Keck, SPT, CMB-S4). 2025 APS Fellow; 2022 Moore EPII award. Director KICP.