David Maresca's lab pushes the boundaries of biomedical ultrasound imaging. Research: (1) functional ultrasound imaging of the brain at cellular resolution (vascular signal decoding, brain-computer interface applications); (2) engineering gas vesicle and microbubble acoustic contrast agents as genetically-encoded biosensors; (3) ultrafast ultrasound for cardiac imaging. The lab aims to image individual cells deep inside living organs using next-generation ultrasound. NWO Vici Grant (2026); Chan Zuckerberg Initiative Dynamic Imaging grant.
Bruce (Jun-Yu) Ou's group applies nanomechanics and nanophotonics to quantum sensor manipulation and AI hardware. Research: (1) ultracompact nanomechanical imaging optics for quantum sensor readout; (2) energy-efficient photonic AI hardware; (3) nanomechanical resonators for force sensing at the quantum limit; (4) nanophotonic interfaces to quantum sensors. Relevant to quantum sensor miniaturisation and readout.
Renaud develops nonlinear and single-sided ultrasound methods to characterize bone and vascular tissue in vivo — quantifying cortical bone porosity, blood-flow, and microbubble/microcrack acoustic signatures — and collaborates closely with David Maresca's functional-ultrasound group on transcranial aberration-corrected Doppler imaging of the brain. This acoustic biosensing work extends the lab's push toward higher-sensitivity, non-invasive acoustic biomarkers analogous in spirit to other quantum-adjacent biosensing modalities.
Willy Supatto (DR2 CNRS, LOB) develops ultrafast two-photon light-sheet microscopy for quantitative in vivo imaging of embryo development and tissue dynamics. Research: (1) two-photon SPIM (light-sheet) for volumetric live imaging in zebrafish embryos; (2) SHG imaging of fibrillar proteins; (3) polarization-THG microscopy of structural anisotropy; (4) photodamage in multiphoton imaging. Part of key LOB team with Beaurepaire.
Tang develops super-resolution ultrasound imaging (localisation of microbubble contrast agents to resolve microvasculature below the diffraction limit) alongside contrast/functional ultrasound methods, applied to cancer, cardiovascular and neurological imaging.